Endocrine Abstracts

Background: Vascular endothelial growth factor (VEGF) is involved in endothelial dysfunction in hypertension and diabetes. It may play a role in the pathogenesis of diabetic nephropathy and retinopathy. Other various growth factors were found to be involved in the neovascularization in proliferative diabetic retinopathy including insulin like growth factor -1 (IGF-1) but most of the studies have measured only a single growth factor especially in the vitreous fluid, thus ignori...

Introduction: Increased visceral adiposity is usually associated with a clustering of atherogenic risk factors, such as insulin resistance, hypertension, dyslipidemia, alterations in coagulation and inflammatory cytokine profiles. Visceral adipose tissue derived serpin (Vaspin) is an adipokine with insulin sensitizing effect which is markedly elevated in high body mass index (BMI) people.Aim: To evaluate serum Vaspin level in relation to atherogenic risk...